Diabetes Hipertensi
Angiotensin ii receptor blockers also show promise in the treatment of hypertension in diabetes. in many patients, a combination of two or more of these agents is necessary to reach blood pressure goals. beta blockers have been shown to reduce cardiovascular risk; however, because of their diabetogenic potential, jnc vi classifies beta blockers as agents that may have unfavorable effects in patients with diabetes. regardless of the agents selected, a reduction in blood pressure helps to prevent diabetic complications. 8 recently, a meta-analysis of trials evaluating the use of antihypertensives in high-risk patients, including those with diabetes, showed that ace inhibitor therapy resulted in a 20 to 30 percent decrease in the risk of stroke, coronary heart disease, and major cardiovascular events. 15 [evidence level a, meta-analysis] thiazide diuretics have been shown to benefit patients with diabetes and systolic hypertension. the systolic hypertension in the elderly program trial wa...